O que se observa é um valor de crescimento estatural final em torno de 85 a 95% do alvo genético, este é um dos motivos que alguns pesquisadores sugerem que mesmo estando dentro do percentil correto da curva de crescimento, eventualmente a criança, infantil, juvenil e adolescente poderá alcançar a máxima da carga genética em se estimulando através das terapêuticas disponíveis incluídos o GH-hormônio de crescimento, principalmente os board-lines. Como consequência, as condições em que ocorre o crescimento em cada momento da vida da criança, infantil, juvenil, incluindo o período intrauterino, determinam as suas possibilidades de atingir ou não seu potencial máximo de crescimento, dotado por sua carga genética e fatores ambientais pós-natal. Na puberdade o final na taxa de crescimento ocorre quando as epífises e dos ossos longos fundem-se e o crescimento cessa.
NORMAL HEIGHT AND LOW HEIGHT AFTER NEWBORN AS VARIATIONS OF LONGITUDINAL GROWTH;DR.CAIO JR./DRA.CAIO.
GROWTH AFTER BIRTH IN HEIGHT FOLLOWS A PATTERN TYPICAL ON NORMAL CHILD, JUVENILE AND ADOLESCENT. LARGEST GLOBAL GROWTH RATE IN FETUS OCCURS, THE GREATEST GROWTH RATE AFTER BIRTH SOON AND FOLLOW UP A SMALL GROWTH RATE IN HALF OF CHILDHOOD, HOWEVER NOT ALWAYS RATE THIS MINOR CHILD GROW AND CHILD IS A SIGN OF NORMAL AND SHOULD BE ANALYZED BY ENDOCRINOLOGIST. PHYSIOLOGY-ENDOCRINOLOGY-NEUROENDOCRINOLOGY-GENETICS-ENDOCRINE-PEDIATRICS (SUBDIVISION OF ENDOCRINOLOGY): DR. JOÃO SANTOS CAIO JR. ET DRA. HENRIQUETA V. CAIO.
There are two periods characterized by brief spurts of growth in infancy: the growth spurt between 1 and ½ year and 3 years of age and the growth spurt between 4 and 8 years old. The growth spurt in middle childhood does not occur in all infants and children, being more frequent in boys than in girls and their occurrence is inherited (parental).
In general growth is a biological process of multiplication and increase in cell size, expressed by the increase of the body size. Every individual is born with a genetic potential for growth, which may or may not be achieved depending on the conditions of life to which it is submitted from conception to adulthood. Therefore, one can say that the growth is influenced by intrinsic factors (genetic, metabolic and malformations often correlated ,e.g. , may be genetically determined) and extrinsic factors, among which stand out the food, health, hygiene, biopsychosocial problems, exercises when appropriate, housing and general care for the child. After another plateau , there is a significant increase in height and follows the growth spurt of puberty, causing a second peak in the rate of linear increase, however, this phase should be very careful several variations that can occur : the outbreak can be fast but not long as the longitudinal increase, leading to a idiopathic short stature, in other words, the expected spurt that depends on a constellation including genetic variants. One detail that is important can be established, e.g., recent research has shown that rarely achieves great from genetically possible target, e.g., 100% capacity growth taking into account all intercurrent factors. What is observed is a value growth of final height around from 85 to 95% of the genetic target, this is one reason that some researchers suggest that although within the correct percentile growth curve eventually the child, infant and adolescent can achieve maximum genetic load is stimulating through the available therapies included GH-growth hormone, mostly board-lines. As a result, the conditions in which growth occurs, in each moment of the juvenile child, including the intrauterine period, determine their chances of achieving or not its maximum growth potential, endowed by their genetic background and environmental factors postnatal. At the end of puberty in growth rate occurs until the epiphysis of the long bones fuse and growth ceases.
Dr. João Santos Caio Jr.
Endocrinologia – Neuroendocrinologista
CRM 20611
Dra. Henriqueta V. Caio
Endocrinologista – Medicina Interna
CRM 28930
1. Em que pese uma importante variabilidade na época de aparecimento dos núcleos de ossificação (vide em seguida), a ordem de aparecimento é bastante constante...
http://hormoniocrescimentoadultos.blogspot.com.
2. Para as mãos e punhos (30 centros) a ordem de início da ossificação dos centros é a seguinte O último núcleo é o correspondente ao sesamóide do adutor do polegar...
http://longevidadefutura.blogspot.com
3. O fato da IO–idade óssea ser determinada por comparação com padrões preestabelecidos, e de serem estes geralmente os apresentados por Greülich & Pyle, podem ser questionáveis...
http://imcobesidade.blogspot.com
AUTORIZADO O USO DOS DIREITOS AUTORAIS COM CITAÇÃO
DOS AUTORES PROSPECTIVOS ET REFERÊNCIA BIBLIOGRÁFICA.
Referências Bibliográficas:
Caio Jr, João Santos, Dr.; Endocrinologista, Neuroendocrinologista, Caio, H. V., Dra. Endocrinologista, Medicina Interna – Van Der Häägen Brazil, São Paulo, Brasil; Alberch, P., Gould, S.J., Oster, G. & Wake, D. 1979. Size and shape in ontogeny and phylogeny. Paleobiology 5: 296±317; Alberch, P. 1982. Developmental constraints in evolutionary processes. In: Evolution and Development (J. T. Bonner, ed.),pp. 313±332. Springer-Verlag, Berlin. Atchley, W.R. 1987. Developmental quantitative genetics and the evolution of ontogenies. Evolution 41: 316±330; Atchley, W.R. & Rutledge, J.J. 1980. Genetic components of size and shape. I. Dynamics of components of phenotypic variability and covariability during ontogeny in the laboratory rat. Evolution 34: 1161±1173; Atchley, W.R., Xu, S. & Cowley, D.E. 1997. Altering developmental trajectories in mice by restricted index selection. Genetics 146: 629±640; Badyaev, A.V. 1993. Breeding biology of the gold-fronted serin (Serinus pusillus) in a subalpine zone of Pamir Mountains.Biol.Sciences (Biol. Nauk) 348: 89±99; Badyaev, A.V. 1994. Breeding biology of white-winged grosbeak (Mycerobas carnipes) in the Pamir Mountains.Bull. MOIP (Biol.Div.)99: 20±28; Badyaev, A.V. 1997a. Avian life history variation along altitudinal gradients: an example with Cardueline Ænches. Oecologia 111: 357±364; Badyaev, A.V. 1997b. Covariation between sexually selected and life history traits: an example with Cardueline Ænches.Oikos 80: 128±138; Badyaev, A.V. & Ghalambor, C.K. 1998. Does a trade-off exist between sexual ornamentation and ecological plasticity?Sexual dichromatism and occupied elevational range in Ænches.Oikos 82: 319±325.
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